- Alendronic acid 70 mg
- Vitamin D3 2800 I.U.
Mechanism of action
Alendronic acid 70mg
- Inhibition of Osteoclast genesis.
- Shortening of OC survival.
- Inhibiting the vitality of ruffled borders.
Vitamin D3 2800 IU
- Is an essential nutrient needed by the body to help absorb calcium from food.
- It is also essential for healthy bones
One tablet Once weekly
- Treatment of postmenopausal osteoporosis
- in patients at risk of vitamin D insufficiency.
- Reduces the risk of vertebral and hip fractures.
- Treatment and reduction of risk of glucocorticoid induced osteoporosis in postmenopausal women not receiving estrogen.
- Hypersensitivity to the active ingredients.
- Abnormalities of the esophagus and other factors which delay esophageal empting such as stricture.
- Inability to stand or sit upright for at least 30 minutes.
- Calcium supplements, and antacids will interfere with Alendronate.
- Therefore, patients must wait at least 30 minutes after taking Alendronate before taking any other medical product.
- Olestra(used in the preparation of traditionally high-fat foods), mineral oils, orlistat, and bile acid like cholestyramine may impair the absorption of vitamin D3.
Pregnancy and lactation:
- No studies on pregnancy and lactation and should not been given to them.
- No age related difference in the efficacy or safety profiles of Alendronate, so no dose adjustment for them.
- It is not recommended for patients with renal impairment where glomerular filtration rate is less than 35 ml/min, due to lack of experience.
N.B. GFR is a test used to detect that kidney working correctly, normal value 90-110ml/min,
- If < 60 means renal disease,
- If < 35 means renal impairment,
- If < 15 means kidney have stopped working .
- No dose adjustment is necessary for patients with GFR greater than 35 ml/min.
- Dose and Administration
- One tablet once weekly.
- If miss a dose , patient should take one tablet on the morning after they remember.
- Must be taken with water only (not mineral water or juice) at least 30 minutes before the first food.
- Should only be swallowed after getting up for the day with a full glass of water (not less than 200 ml)
- Patients should not lie down for at least 30 minutes after taking Alendomax plus
Package and price
- Alendomax Plus Box : 1 strip