Alendomax plus


  • Alendronic acid 70 mg
  • Vitamin D3 2800 I.U.


Mechanism of action

  Alendronic acid 70mg

  • Inhibition of Osteoclast genesis.
  • Shortening of OC survival.
  • Inhibiting the vitality of ruffled borders.


  Vitamin D3 2800 IU

  • Is an essential nutrient needed by the body to help absorb calcium from food.
  • It is also essential for healthy bones



             One tablet Once weekly      



  • Treatment of postmenopausal osteoporosis 


  • in patients at risk of vitamin D insufficiency.


  • Reduces the risk of vertebral and hip fractures.


  • Treatment and reduction of risk of glucocorticoid induced osteoporosis in postmenopausal women not receiving estrogen.




  • Hypersensitivity to the active ingredients.


  • Abnormalities of the esophagus and other factors which delay esophageal empting such as stricture.


  • Inability to stand or sit upright for at least 30 minutes.




Drug-Drug interactions


  • Calcium supplements, and antacids will interfere with Alendronate.
  • Therefore, patients must wait at least 30 minutes after taking Alendronate before taking any other medical product.


  • Olestra(used in the preparation of traditionally high-fat foods), mineral oils, orlistat, and bile acid like cholestyramine may impair the absorption of vitamin D3.



Special populations


Pregnancy and lactation:

  • No studies on pregnancy and lactation and should not been given to them.


Elderly population:

  • No age related difference in the efficacy or safety profiles of Alendronate, so no dose adjustment for them.


Renal impairment:


  • It is not recommended for patients with renal impairment where glomerular filtration rate is less than 35 ml/min, due to lack of experience.

N.B.   GFR is a test used to detect that kidney working correctly, normal value 90-110ml/min,

  • If < 60 means renal disease,
  • If < 35 means renal impairment,
  • If < 15 means kidney have stopped working .


  • No dose adjustment is necessary for patients with GFR greater than 35 ml/min.



  • Dose and Administration
  • One tablet once weekly.


  • If miss a dose , patient should take one tablet on the morning after they remember.


  • Must be taken with water only (not mineral water or juice) at least 30 minutes before the first food.


  • Should only be swallowed after getting up for the day with a full glass of water (not less than 200 ml)


  • Patients should not lie down for at least 30 minutes after taking Alendomax plus



Package and price


  • Alendomax Plus Box :   1 strip


  • 2 tablets.